Project Chimera scientists try to figure out a way to give Charlie Wilde and her friends new powers from the animal kingdom to use against Dr. Gray and his followers, who are bent on transforming humanity into a monstrous new species, subservient to them.
When they are separated at sea, mouse siblings Clarice and Charles Sebastian, who were taught to be careful, must now need to be bold if they are to survive-- and keep their promise to find one another again.